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ARIEL and AMELIA: Testing for an Accumulation of Rare Variants Using Next-Generation Sequencing Data
OBJECTIVES: There is increasing evidence that rare variants play a role in some complex traits, but their analysis is not straightforward. Locus-based tests become necessary due to low power in rare variant single-point association analyses. In addition, variant quality scores are available for sequ...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477640/ https://ncbi.nlm.nih.gov/pubmed/22441326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000336982 |
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