ARIEL and AMELIA: Testing for an Accumulation of Rare Variants Using Next-Generation Sequencing Data

OBJECTIVES: There is increasing evidence that rare variants play a role in some complex traits, but their analysis is not straightforward. Locus-based tests become necessary due to low power in rare variant single-point association analyses. In addition, variant quality scores are available for sequ...

Full description

Saved in:
Bibliographic Details
Main Authors: Asimit, Jennifer L., Day-Williams, Aaron G., Morris, Andrew P., Zeggini, Eleftheria
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477640/
https://ncbi.nlm.nih.gov/pubmed/22441326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000336982
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items