A genome-wide 3C-method for characterizing the three-dimensional architectures of genomes

Accumulating evidence demonstrates that the three-dimensional (3D) organization of chromosomes within the eukaryotic nucleus reflects and influences genomic activities, including transcription, DNA replication, recombination and DNA repair. In order to uncover structure-function relationships, it is...

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Bibliographic Details
Main Authors: Duan, Zhijun, Andronescu, Mirela, Schutz, Kevin, Lee, Choli, Shendure, Jay, Fields, Stanley, Noble, William S., Blau, C. Anthony
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477625/
https://ncbi.nlm.nih.gov/pubmed/22776363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2012.06.018
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