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Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology
BACKGROUND: Alzheimer’s disease (AD) is the leading cause of dementia among the elderly. Disease modifying therapies targeting Aβ that are in development have been proposed to be more effective if treatment was initiated prior to significant accumulation of Aβ in the brain, but optimal timing of tre...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477045/ https://ncbi.nlm.nih.gov/pubmed/22892055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-39 |
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