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Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition
BACKGROUND: Pro-inflammatory stimuli, including cytokines like Interleukin-1β, Interleukin-6 and Interferon-γ, in the brain have been proposed to exacerbate existing Alzheimer’s disease (AD) neuropathology by increasing amyloidogenic processing of APP and promoting further Aβ accumulation in AD. On...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3441281/ https://ncbi.nlm.nih.gov/pubmed/22838967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-36 |
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