Combination of Aβ Suppression and Innate Immune Activation in the Brain Significantly Attenuates Amyloid Plaque Deposition

Anti-Aβ clinical trials are currently under way to determine whether preventing amyloid deposition will be beneficial in arresting progression of Alzheimer disease. Both clinical and preclinical studies suggest that antiamyloid strategies are only effective if started at early stages of the disease...

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Publicado en:Am J Pathol
Autores principales: Verbeeck, Christophe, Carrano, Anna, Chakrabarty, Paramita, Jankowsky, Joanna L., Das, Pritam
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718090/
https://ncbi.nlm.nih.gov/pubmed/28919107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.010
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