Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study

Individual cancers harbor a set of genetic aberrations that can be informative for identifying rational therapies currently available or in clinical trials. We implemented a pilot study to explore the practical challenges of applying high-throughput sequencing in clinical oncology. We enrolled patie...

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Hauptverfasser: Roychowdhury, Sameek, Iyer, Matthew K., Robinson, Dan R., Lonigro, Robert J., Wu, Yi-Mi, Cao, Xuhong, Kalyana-Sundaram, Shanker, Sam, Lee, Balbin, O. Alejandro, Quist, Michael J., Barrette, Terrence, Everett, Jessica, Siddiqui, Javed, Kunju, Lakshmi P., Navone, Nora, Araujo, John C., Troncoso, Patricia, Logothetis, Christopher J., Innis, Jeffrey W., Smith, David C., Lao, Christopher D., Kim, Scott Y., Roberts, J. Scott, Gruber, Stephen B., Pienta, Kenneth J., Talpaz, Moshe, Chinnaiyan, Arul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476478/
https://ncbi.nlm.nih.gov/pubmed/22133722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003161
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