Identification of Recurrent NAB2-STAT6 Gene Fusions in Solitary Fibrous Tumor by Integrative Sequencing

A 44-year old woman with recurrent solitary fibrous tumor (SFT)/hemangiopericytoma was enrolled in a clinical sequencing program including whole exome and transcriptome sequencing. A gene fusion of the transcriptional repressor NAB2 with the transcriptional activator STAT6 was detected. Transcriptom...

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Bibliografiske detaljer
Main Authors: Robinson, Dan R., Wu, Yi-Mi, Kalyana-Sundaram, Shanker, Cao, Xuhong, Lonigro, Robert J., Sung, Yun-Shao, Chen, Chun-Liang, Zhang, Lei, Wang, Rui, Su, Fengyun, Iyer, Matthew K., Roychowdhury, Sameek, Siddiqui, Javed, Pienta, Kenneth J., Kunju, Lakshmi P., Talpaz, Moshe, Mosquera, Juan Miguel, Singer, Samuel, Schuetze, Scott M., Antonescu, Cristina R., Chinnaiyan, Arul M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654808/
https://ncbi.nlm.nih.gov/pubmed/23313952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2509
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