Caricamento...

In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling

Replication protein A (RPA) plays essential roles in DNA metabolism, including replication, checkpoint, and repair. Recently, we described an in vitro system in which the phosphorylation of human Chk1 kinase by ATR (ataxia telangiectasia mutated and Rad3-related) is dependent on RPA bound to single-...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lindsey-Boltz, Laura A., Reardon, Joyce T., Wold, Marc S., Sancar, Aziz
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476280/
https://ncbi.nlm.nih.gov/pubmed/22948311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.407825
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !