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Subtype-specific Modulation of Acid-sensing Ion Channel (ASIC) Function by 2-Guanidine-4-methylquinazoline

Acid-sensing ion channels (ASICs) are neuronal Na(+)-selective channels that are transiently activated by extracellular acidification. ASICs are involved in fear and anxiety, learning, neurodegeneration after ischemic stroke, and pain sensation. The small molecule 2-guanidine-4-methylquinazoline (GM...

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Bibliografiske detaljer
Main Authors: Alijevic, Omar, Kellenberger, Stephan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476274/
https://ncbi.nlm.nih.gov/pubmed/22948146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.360487
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