Loading...

Extracellular Chloride Modulates the Desensitization Kinetics of Acid-sensing Ion Channel 1a (ASIC1a)

Acid-sensing ion channels (ASICs) are sodium channels gated by extracellular protons. The recent crystallization of ASIC1a identified potential binding sites for Cl(−) in the extracellular domain that are highly conserved between ASIC isoforms. However, the significance of Cl(−) binding is unknown....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Kusama, Nobuyoshi, Harding, Anne Marie S., Benson, Christopher J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878506/
https://ncbi.nlm.nih.gov/pubmed/20385551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.091561
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!