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The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling
The anterior and intermediate lobes of the pituitary gland derive from the surface ectoderm. They provide a simple system to assess mechanisms of developmental identity established by tissue determinants. Each lobe contains a lineage expressing the hormone precursor pro-opiomelanocortin (POMC): the...
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Main Authors: | , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Cold Spring Harbor Laboratory Press
2012
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475802/ https://ncbi.nlm.nih.gov/pubmed/23070814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.200436.112 |
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