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The Physical Foundation of Vasoocclusion in Sickle Cell Disease

The pathology of sickle cell disease arises from the occlusion of small blood vessels because of polymerization of the sickle hemoglobin within the red cells. We present measurements using a microfluidic method we have developed to determine the pressure required to eject individual red cells from a...

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Main Authors: Aprelev, Alexey, Stephenson, William, Noh, Hongseok (Moses), Meier, Maureen, Ferrone, Frank A.
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475338/
https://ncbi.nlm.nih.gov/pubmed/23083726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.003
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