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The Physical Foundation of Vasoocclusion in Sickle Cell Disease

The pathology of sickle cell disease arises from the occlusion of small blood vessels because of polymerization of the sickle hemoglobin within the red cells. We present measurements using a microfluidic method we have developed to determine the pressure required to eject individual red cells from a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aprelev, Alexey, Stephenson, William, Noh, Hongseok (Moses), Meier, Maureen, Ferrone, Frank A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475338/
https://ncbi.nlm.nih.gov/pubmed/23083726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.003
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