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Ratchets, red cells, and metastability

Sickle cell disease is a genetic disorder in which a negatively charged glutamic acid is replaced by a hydrophobic valine on the surface of the hemoglobin molecule, leading to polymerization of the deoxygenated form, and resulting in microvascular obstruction. Because of the high volume occupancy un...

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Podrobná bibliografie
Vydáno v:Biophys Rev
Hlavní autoři: Ferrone, Frank A., Aprelev, Alexey
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425722/
https://ncbi.nlm.nih.gov/pubmed/28510163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-013-0117-z
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