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Metastable Polymerization of Sickle Hemoglobin in Droplets

Sickle cell disease arises from a genetic mutation of one amino acid in each of the two hemoglobin β chains, leading to the polymerization of hemoglobin in the red cell upon deoxygenation, and is characterized by vascular crises and tissue damage due to the obstruction of small vessels by sickled ce...

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Detaylı Bibliyografya
Asıl Yazarlar: Aprelev, Alexey, Weng, Weijun, Zakharov, Mikhail, Rotter, Maria, Yosmanovich, Donna, Kwong, Suzanna, Briehl, Robin W., Ferrone, Frank A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950749/
https://ncbi.nlm.nih.gov/pubmed/17493634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.04.030
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