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Heterogeneous Nucleation in Sickle Hemoglobin: Experimental Validation of a Structural Mechanism
Sickle hemoglobin polymerizes by two types of nucleation: homogeneous nucleation of aggregates in solution, and heterogeneous nucleation on preexisting polymers. It has been proposed that the same contact that is made in the interior of the polymer between the mutant site β6 and its receptor pocket...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Biophysical Society
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366768/ https://ncbi.nlm.nih.gov/pubmed/16055526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.067785 |
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