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The Effects of Erythrocyte Membranes on the Nucleation of Sickle Hemoglobin
Pathology in sickle cell disease begins with nucleation-dependent polymerization of deoxyhemoglobin S into stiff, rodlike fibers that deform and rigidify red cells. We have measured the effect of erythrocyte membranes on the rate of homogeneous nucleation in sickle hemoglobin, using preparations of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1305376/ https://ncbi.nlm.nih.gov/pubmed/15653736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051086 |
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