The Effects of Erythrocyte Membranes on the Nucleation of Sickle Hemoglobin

Pathology in sickle cell disease begins with nucleation-dependent polymerization of deoxyhemoglobin S into stiff, rodlike fibers that deform and rigidify red cells. We have measured the effect of erythrocyte membranes on the rate of homogeneous nucleation in sickle hemoglobin, using preparations of...

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Detaylı Bibliyografya
Asıl Yazarlar: Aprelev, Alexey, Rotter, Maria A., Etzion, Zipora, Bookchin, Robert M., Briehl, Robin W., Ferrone, Frank A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Biophysical Society 2005
Konular:
Proteins
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305376/
https://ncbi.nlm.nih.gov/pubmed/15653736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051086
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