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Ratchets, red cells, and metastability
Sickle cell disease is a genetic disorder in which a negatively charged glutamic acid is replaced by a hydrophobic valine on the surface of the hemoglobin molecule, leading to polymerization of the deoxygenated form, and resulting in microvascular obstruction. Because of the high volume occupancy un...
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| Pubblicato in: | Biophys Rev |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer-Verlag
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5425722/ https://ncbi.nlm.nih.gov/pubmed/28510163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-013-0117-z |
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