Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism

Nonalcoholic fatty liver disease (NAFLD) is a major health problem and a leading cause of chronic liver disease in the United States and developed countries. In humans, genetic factors greatly influence individual susceptibility to NAFLD. The goals of this study were to compare the magnitude of inte...

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Hlavní autoři: Tryndyak, Volodymyr, de Conti, Aline, Kobets, Tetyana, Kutanzi, Kristy, Koturbash, Igor, Han, Tao, Fuscoe, James C., Latendresse, John R., Melnyk, Stepan, Shymonyak, Svitlana, Collins, Leonard, Ross, Sharon A., Rusyn, Ivan, Beland, Frederick A., Pogribny, Igor P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2012
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475259/
https://ncbi.nlm.nih.gov/pubmed/22872676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-209569
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