Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum

The molecular pathogenesis of autism is complex and involves numerous genomic, epigenomic, proteomic, metabolic, and physiological alterations. Elucidating and understanding the molecular processes underlying the pathogenesis of autism is critical for effective clinical management and prevention of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shpyleva, Svitlana, Ivanovsky, Samuil, de Conti, Aline, Melnyk, Stepan, Tryndyak, Volodymyr, Beland, Frederick A., James, S. Jill, Pogribny, Igor P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244134/
https://ncbi.nlm.nih.gov/pubmed/25423485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113712
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