Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum

The molecular pathogenesis of autism is complex and involves numerous genomic, epigenomic, proteomic, metabolic, and physiological alterations. Elucidating and understanding the molecular processes underlying the pathogenesis of autism is critical for effective clinical management and prevention of...

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Publicat a:PLoS One
Autors principals: Shpyleva, Svitlana, Ivanovsky, Samuil, de Conti, Aline, Melnyk, Stepan, Tryndyak, Volodymyr, Beland, Frederick A., James, S. Jill, Pogribny, Igor P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244134/
https://ncbi.nlm.nih.gov/pubmed/25423485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113712
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