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Mechanisms of peroxisome proliferator-induced DNA hypomethylation in rat liver

Genomic hypomethylation is a consistent finding in both human and animal tumors and mounting experimental evidence suggests a key role for epigenetic events in tumorigenesis. Furthermore, it has been suggested that early changes in DNA methylation and histone modifications may serve as sensitive pre...

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Detalhes bibliográficos
Main Authors: Pogribny, Igor P., Tryndyak, Volodymyr P., Boureiko, Anna, Melnyk, Stepan, Bagnyukova, Tetyana V., Montgomery, Beverly, Rusyn, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571982/
https://ncbi.nlm.nih.gov/pubmed/18639561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2008.06.009
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