Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

BACKGROUND/AIMS: The importance of epigenetic changes in etiology and pathogenesis of disease has been increasingly recognized. However, the role of epigenetic alterations in the genesis of hepatic steatosis and cause of individual susceptibilities to this pathological state are largely unknown. MET...

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Huvudupphovsmän: Pogribny, Igor P., Tryndyak, Volodymyr P., Bagnyukova, Tetyana V., Melnyk, Stepan, Montgomery, Beverly, Ross, Sharon A., Latendresse, John R., Rusyn, Ivan, Beland, Frederick A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773516/
https://ncbi.nlm.nih.gov/pubmed/19450891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.03.021
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