Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

BACKGROUND/AIMS: The importance of epigenetic changes in etiology and pathogenesis of disease has been increasingly recognized. However, the role of epigenetic alterations in the genesis of hepatic steatosis and cause of individual susceptibilities to this pathological state are largely unknown. MET...

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Main Authors: Pogribny, Igor P., Tryndyak, Volodymyr P., Bagnyukova, Tetyana V., Melnyk, Stepan, Montgomery, Beverly, Ross, Sharon A., Latendresse, John R., Rusyn, Ivan, Beland, Frederick A.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773516/
https://ncbi.nlm.nih.gov/pubmed/19450891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.03.021
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