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Effects of Ethanol on Conformational Changes of Akt Studied by Chemical Cross-Linking, Mass Spectrometry, and (18)O Labeling

[Image: see text] Although PI3K/Akt signaling that regulates neuronal survival has been implicated in the deleterious effects of ethanol on the central nervous system, underlying molecular mechanisms have not been fully elucidated. Akt–membrane interaction is a prerequisite step for Akt activation s...

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Detalhes bibliográficos
Main Authors: Huang, Bill X., Kim, Hee-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475205/
https://ncbi.nlm.nih.gov/pubmed/22129086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2003237
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