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Conformational Changes Involved in G Protein-coupled Receptor Activation

Little is known about the nature of the conformational changes that convert G protein-coupled receptors (GPCRs), which bind diffusible ligands, from their resting into their active states. To gain structural insight into this process, various laboratories have used disulfide cross-linking strategies...

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書目詳細資料
Main Authors: Wess, Jürgen, Han, Sung-Jun, Kim, Soo-Kyung, Jacobson, Kenneth A., Li, Jian Hua
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475190/
https://ncbi.nlm.nih.gov/pubmed/18838178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2008.08.006
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