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Nucleic-Acid-Binding Chromophores as Efficient Indicators of Aptamer-Target Interactions

The binding affinity and specificity of nucleic acid aptamers have made them valuable candidates for use as sensors in diagnostic applications. In particular, chromophore-functionalized aptamers offer a relatively simple format for detection and quantification of target molecules. We describe the us...

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Detalhes bibliográficos
Main Authors: Sarpong, Kwabena, Datta, Bhaskar
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474971/
https://ncbi.nlm.nih.gov/pubmed/23094140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/247280
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