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Are Circulating Metabolites Important in Drug-Drug Interactions? Quantitative Analysis of Risk Prediction and Inhibitory Potency
The potential of metabolites to contribute to drug-drug interactions is not well defined. The aim of this study was to determine the quantitative role of circulating metabolites in inhibitory drug-drug interactions in vivo. The AUC data for at least one circulating metabolite was available for 71% o...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474849/ https://ncbi.nlm.nih.gov/pubmed/21124313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2010.252 |
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