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Qualitative Analysis of the Role of Metabolites in Inhibitory Drug-Drug Interactions: Literature Evaluation Based on the Metabolism and Transport Drug Interaction Database

Guidance from the Food and Drug Administration on drug interaction studies does not include a specific section on contributions of metabolites to observed inhibitory drug-drug interactions, and the quantitative role of drug metabolites in inhibitory drug-drug interactions is not presently known. The...

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Hlavní autoři: Isoherranen, Nina, Hachad, Houda, Yeung, Catherine K, Levy, Rene H
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755268/
https://ncbi.nlm.nih.gov/pubmed/19216580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800491e
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