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Establishment of Inducible Wild Type and Mutant Myocilin-GFP-Expressing RGC5 Cell Lines

BACKGROUND: Myocilin is a gene linked directly to juvenile- and adult-onset open angle glaucoma. Mutations including Gln368stop (Q368X) and Pro370Leu (P370L) have been identified in patients. The exact role of myocilin and its functional association with glaucoma are still unclear. In the present st...

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Autori principali: Ying, Hongyu, Shen, Xiang, Yue, Beatrice Y. J. T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474840/
https://ncbi.nlm.nih.gov/pubmed/23082156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047307
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