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Establishment of Inducible Wild Type and Mutant Myocilin-GFP-Expressing RGC5 Cell Lines

BACKGROUND: Myocilin is a gene linked directly to juvenile- and adult-onset open angle glaucoma. Mutations including Gln368stop (Q368X) and Pro370Leu (P370L) have been identified in patients. The exact role of myocilin and its functional association with glaucoma are still unclear. In the present st...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ying, Hongyu, Shen, Xiang, Yue, Beatrice Y. J. T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474840/
https://ncbi.nlm.nih.gov/pubmed/23082156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047307
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