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Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells
Cancer can be envisioned as a metabolic disease driven by pressure selection and intercellular cooperativeness. Together with anaerobic glycolysis, the Warburg effect, formally corresponding to uncoupling glycolysis from oxidative phosphorylation, directly participates in cancer aggressiveness, supp...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474765/ https://ncbi.nlm.nih.gov/pubmed/23082126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046571 |
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