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Lactate does not activate NF-κB in oxidative tumor cells
The lactate anion is currently emerging as an oncometabolite. Lactate, produced and exported by glycolytic and glutaminolytic cells in tumors, can be recycled as an oxidative fuel by oxidative tumors cells. Independently of hypoxia, it can also activate transcription factor hypoxia-inducible factor-...
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| Vydáno v: | Front Pharmacol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4602127/ https://ncbi.nlm.nih.gov/pubmed/26528183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00228 |
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