Lactate promotes glutamine uptake and metabolism in oxidative cancer cells

Oxygenated cancer cells have a high metabolic plasticity as they can use glucose, glutamine and lactate as main substrates to support their bioenergetic and biosynthetic activities. Metabolic optimization requires integration. While glycolysis and glutaminolysis can cooperate to support cellular pro...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Pérez-Escuredo, Jhudit, Dadhich, Rajesh K, Dhup, Suveera, Cacace, Andrea, Van Hée, Vincent F, De Saedeleer, Christophe J, Sboarina, Martina, Rodriguez, Fabien, Fontenille, Marie-Joséphine, Brisson, Lucie, Porporato, Paolo E, Sonveaux, Pierre
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825768/
https://ncbi.nlm.nih.gov/pubmed/26636483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1120930
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