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Selective Gelatinase Inhibitor Neuroprotective Agents Cross the Blood-Brain Barrier

[Image: see text] SB-3CT, a potent and selective inhibitor of matrix metalloproteinase-2 and -9, has shown efficacy in several animal models of neurological diseases. One of the greatest challenges in the development of therapeutics for neurological diseases is the inability of drugs to cross the bl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gooyit, Major, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Mobashery, Shahriar, Chang, Mayland
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2012
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474282/
https://ncbi.nlm.nih.gov/pubmed/23077716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300062w
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