Molecular and cellular pathogenesis of hemoglobin SC disease.

Solution and cell studies were performed to ascertain why individuals with hemoglobin (Hb) SC have disease whereas those with Hb AS do not. The polymerization of deoxygenated mixtures containing sickle cell Hb (Hb S; alpha 2 beta 2(6)Glu leads to Val) and Hb C (alpha 2 beta 2(6)Glu leads to Lys) was...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Bunn, H F, Noguchi, C T, Hofrichter, J, Schechter, G P, Schechter, A N, Eaton, W A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1982
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6961429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7527
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