Molecular and cellular pathogenesis of hemoglobin SC disease.

Solution and cell studies were performed to ascertain why individuals with hemoglobin (Hb) SC have disease whereas those with Hb AS do not. The polymerization of deoxygenated mixtures containing sickle cell Hb (Hb S; alpha 2 beta 2(6)Glu leads to Val) and Hb C (alpha 2 beta 2(6)Glu leads to Lys) was...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Bunn, H F, Noguchi, C T, Hofrichter, J, Schechter, G P, Schechter, A N, Eaton, W A
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1982
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6961429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7527
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