Investigation of Cortical Glutamate–Glutamine and γ-Aminobutyric Acid in Obsessive–Compulsive Disorder by Proton Magnetic Resonance Spectroscopy

Glutamatergic abnormalities in corticostriatal brain circuits are thought to underlie obsessive–compulsive disorder (OCD). Whether these abnormalities exist in adults with OCD is not clear. We used proton magnetic resonance spectroscopy ((1)H MRS) to test our hypothesis that unmedicated adults with...

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Autors principals: Simpson, Helen B, Shungu, Dikoma C, Bender, James, Mao, Xiangling, Xu, Xiaoyan, Slifstein, Mark, Kegeles, Lawrence S
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473334/
https://ncbi.nlm.nih.gov/pubmed/22850733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.132
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