Investigation of Cortical Glutamate–Glutamine and γ-Aminobutyric Acid in Obsessive–Compulsive Disorder by Proton Magnetic Resonance Spectroscopy

Glutamatergic abnormalities in corticostriatal brain circuits are thought to underlie obsessive–compulsive disorder (OCD). Whether these abnormalities exist in adults with OCD is not clear. We used proton magnetic resonance spectroscopy ((1)H MRS) to test our hypothesis that unmedicated adults with...

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Hlavní autoři: Simpson, Helen B, Shungu, Dikoma C, Bender, James, Mao, Xiangling, Xu, Xiaoyan, Slifstein, Mark, Kegeles, Lawrence S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473334/
https://ncbi.nlm.nih.gov/pubmed/22850733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.132
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