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Manganese toxicity in the CNS: the glutamine/glutamate-γ-aminobutyric acid cycle

Manganese (Mn) is an essential trace element that is required for maintaining proper function and regulation of numerous biochemical and cellular reactions. Despite its essentiality, at excessive levels Mn is toxic to the CNS. Increased accumulation of Mn in specific brain regions, such as the subst...

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Detalhes bibliográficos
Main Authors: Sidoryk-Wegrzynowicz, Marta, Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633698/
https://ncbi.nlm.nih.gov/pubmed/23360507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.12040
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