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Manganese toxicity in the CNS: the glutamine/glutamate-γ-aminobutyric acid cycle

Manganese (Mn) is an essential trace element that is required for maintaining proper function and regulation of numerous biochemical and cellular reactions. Despite its essentiality, at excessive levels Mn is toxic to the CNS. Increased accumulation of Mn in specific brain regions, such as the subst...

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Autors principals: Sidoryk-Wegrzynowicz, Marta, Aschner, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633698/
https://ncbi.nlm.nih.gov/pubmed/23360507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.12040
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