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Manganese toxicity in the CNS: the glutamine/glutamate-γ-aminobutyric acid cycle
Manganese (Mn) is an essential trace element that is required for maintaining proper function and regulation of numerous biochemical and cellular reactions. Despite its essentiality, at excessive levels Mn is toxic to the CNS. Increased accumulation of Mn in specific brain regions, such as the subst...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633698/ https://ncbi.nlm.nih.gov/pubmed/23360507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.12040 |
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