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Manganese toxicity in the CNS: the glutamine/glutamate-γ-aminobutyric acid cycle

Manganese (Mn) is an essential trace element that is required for maintaining proper function and regulation of numerous biochemical and cellular reactions. Despite its essentiality, at excessive levels Mn is toxic to the CNS. Increased accumulation of Mn in specific brain regions, such as the subst...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sidoryk-Wegrzynowicz, Marta, Aschner, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633698/
https://ncbi.nlm.nih.gov/pubmed/23360507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.12040
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