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Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action.

Antibodies to the insulin receptor were prepared in BALB/c mice by immunization with IM-9 human lymphocytes, a cell type that has a large number of plasma membrane insulin receptors. The spleens of these mice were then removed, and their lymphocytes were fused to a mouse myeloma cell line, FO cells....

詳細記述

保存先:
書誌詳細
主要な著者: Roth, R A, Cassell, D J, Wong, K Y, Maddux, B A, Goldfine, I D
フォーマット: Artigo
言語:Inglês
出版事項: 1982
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC347329/
https://ncbi.nlm.nih.gov/pubmed/6185950
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