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Protein tyrosine phosphatase Shp2 (Ptpn11) plays an important role in maintenance of chromosome stability

Both activating and inactivating mutations in protein tyrosine phosphatase Ptpn11 (encoding Shp2) are associated with tumorigenesis. However, the underlying mechanisms remain unclear. Here we demonstrate that Shp2 plays an important role in mitosis, dysregulation of which results in chromosome insta...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Liu, Xia, Zheng, Hong, Qu, Cheng-Kui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473170/
https://ncbi.nlm.nih.gov/pubmed/22890240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1495
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