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Adoptive Transfer of Cytotoxic T Lymphocytes Targeting Two Different Antigens Limits Antigen Loss and Tumor Escape

An antitumor T-cell response can lead to tumor control without clearing all tumor cells. As long as residual tumor cells remain, there is a constant risk of escape from that T-cell response. We previously showed that adoptive transfer of anti-ova OT-I T cells into B16ova-bearing mice led to tumor re...

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Détails bibliographiques
Auteurs principaux: Kaluza, Karen M., Kottke, Timothy, Diaz, Rosa Maria, Rommelfanger, Diana, Thompson, Jill, Vile, Richard
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472520/
https://ncbi.nlm.nih.gov/pubmed/22734672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.030
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