Activating Systemic T-Cell Immunity Against Self Tumor Antigens to Support Oncolytic Virotherapy with Vesicular Stomatitis Virus

We have shown that the antitumor activity of vesicular stomatitis virus (VSV) against B16ova tumors in C57BL/6 mice is predominantly due to innate antiviral immune effectors. We have also shown that the innate immune-activating properties of VSV can be harnessed to prime adaptive T-cell responses ag...

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Detalhes bibliográficos
Main Authors: Wongthida, Phonphimon, Diaz, Rosa Maria, Pulido, Christine, Rommelfanger, Diana, Galivo, Feorillo, Kaluza, Karen, Kottke, Timothy, Thompson, Jill, Melcher, Alan, Vile, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225040/
https://ncbi.nlm.nih.gov/pubmed/21366404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.216
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