Type III IFN Interleukin-28 Mediates the Antitumor Efficacy of Oncolytic Virus VSV in Immune-Competent Mouse Models of Cancer

Innate immune effector mechanisms triggered by oncolytic viruses may contribute to the clearance of both infected and uninfected tumor cells in immunocompetent murine hosts. Here, we developed an in vitro tumor cell/bone marrow coculture assay and used it to dissect innate immune sensor and effector...

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Hlavní autoři: Wongthida, Phonphimon, Diaz, Rosa Maria, Galivo, Feorillo, Kottke, Timothy, Thompson, Jill, Pulido, Jose, Pavelko, Kevin, Pease, Larry, Melcher, Alan, Vile, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896099/
https://ncbi.nlm.nih.gov/pubmed/20484025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4658
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