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Adoptive T cell therapy promotes the emergence of genomically altered tumor escape variants

Adoptive T cell therapy has proven effective against melanoma in mice and humans. However, because most responses are incomplete or transient, cures remain rare. To maximize the efficacy of this therapy, it will be essential to gain a better understanding of the processes which result in tumor relap...

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Detalhes bibliográficos
Main Authors: Kaluza, Karen M., Thompson, Jill M., Kottke, Timothy J., Flynn Gilmer, Heather C., Knutson, Darlene L., Vile, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903054/
https://ncbi.nlm.nih.gov/pubmed/21935923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26447
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