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Adoptive T cell therapy promotes the emergence of genomically altered tumor escape variants

Adoptive T cell therapy has proven effective against melanoma in mice and humans. However, because most responses are incomplete or transient, cures remain rare. To maximize the efficacy of this therapy, it will be essential to gain a better understanding of the processes which result in tumor relap...

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Bibliografiske detaljer
Main Authors: Kaluza, Karen M., Thompson, Jill M., Kottke, Timothy J., Flynn Gilmer, Heather C., Knutson, Darlene L., Vile, Richard G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903054/
https://ncbi.nlm.nih.gov/pubmed/21935923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26447
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