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Fucosylation Enhances the Efficacy of Adoptively Transferred Antigen-specific Cytotoxic T Lymphocytes
PURPOSE: Inefficient homing of adoptively transferred cytotoxic T lymphocytes (CTLs) to tumors is a major limitation to the efficacy of adoptive cellular therapy (ACT) for cancer. However, through fucosylation, a process whereby fucosyltransferases (FTs) add fucose groups to cell surface glycoprotei...
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| Publicado no: | Clin Cancer Res |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467811/ https://ncbi.nlm.nih.gov/pubmed/30647079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1527 |
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