Binding and Translocation of Termination Factor Rho Studied at the Single-Molecule Level

Rho termination factor is an essential hexameric helicase responsible for terminating 20–50% of all mRNA synthesis in E. coli. We used single- molecule force spectroscopy to investigate Rho-RNA binding interactions at the Rho- utilization (rut) site of the ? tR1 terminator. Our results are consisten...

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Hlavní autoři: Koslover, Daniel J., Fazal, Furqan M., Mooney, Rachel A., Landick, Robert, Block, Steven M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472157/
https://ncbi.nlm.nih.gov/pubmed/22885804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.07.027
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